Anti-GBF1 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q92538

This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene.

GBF1

Rabbit polyclonal against GBF1

Golgi Apparatus
Cis-Golgi Network
Endoplasmic Reticulum-Golgi Intermediate Compartment
Trans-Golgi Network
Cytoplasm
Lipid Droplet
Membrane
Peripheral Membrane Protein
Cycles Rapidly On And Off Early Golgi Membranes
Stabilized On Membranes When Complexed With Arf1-Gdp And Is Released From Both Arf1 And Membranes After It Catalyzes Gdp Displacement And Arf1 Binds Gtp
Continuous Cycles Of Recruitment And Dissociation Of Gbf1 To Membranes Are Required For Sustained Arf Activation And Cop I Recruitment
In Neutrophils Is Translocated From The Golgi To The Leading Edge Upon Gpcr Stimulation
Localization To Lipid Droplets Is Questionable

WB 1:500-1:2000

Golgi-Specific Brefeldin A-Resistance Guanine Nucleotide Exchange Factor 1
Bfa-Resistant Gef 1

GBF1_HUMAN