Item no. |
STJ114398-100 |
Manufacturer |
St John's Laboratory
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IP, IHC |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Dna Topoisomerase 1 antibody</br>Anti-Dna Topoisomerase I antibody</br>Anti-TOP1 antibody |
Similar products |
Anti-Dna Topoisomerase 1 antibodyAnti-Dna Topoisomerase I antibodyAnti-TOP1 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P11387 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. |
Gene ID |
|
Gene symbol |
|
Immunogen |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TOP1 (NP_003277. 1). |
Short Description |
Rabbit polyclonal against TOP1 |
Tissue specificity |
Endothelial cells. |
Cellular localization |
NucleusNucleolusNucleoplasmDiffuse Nuclear Localization With Some Enrichment In NucleoliOn Cpt TreatmentCleared From Nucleoli Into NucleoplasmSumoylated Forms Found In Both Nucleoplasm And Nucleoli |
Molecular weight |
Calculated: 90kDa. Observed: 120kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 IP 1:20-1:50 |
Alternative names |
Anti-Dna Topoisomerase 1 antibodyAnti-Dna Topoisomerase I antibodyAnti-TOP1 antibody |
Protein name |
Dna Topoisomerase 1Dna Topoisomerase I |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.