Anti-MAPK14 antibody (1-360) (STJ113086)

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q16539

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

MAPK14

Rabbit polyclonal against MAPK14

Cytoplasm
Nucleus

WB 1:500-1:2000 IHC 1:50-1:100

Mitogen-Activated Protein Kinase 14
Map Kinase 14
Mapk 14
Cytokine Suppressive Anti-Inflammatory Drug-Binding Protein
Csaid-Binding Protein
Csbp
Map Kinase Mxi2
Max-Interacting Protein 2
Mitogen-Activated Protein Kinase P38 Alpha
Map Kinase P38 Alpha
Stress-Activated Protein Kinase 2a
Sapk2a

MK14_HUMAN