Item no. |
STJ113086-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50 ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Mitogen-Activated Protein Kinase 14 antibody</br>Anti-Map Kinase 14 antibody</br>Anti-Mapk 14 antibody</br>Anti-Cytokine Suppressive Anti-Inflammatory Drug-Binding Protein antibody</br>Anti-Csaid-Binding Protein antibody</br>Anti-Csbp antibody</br>An |
Similar products |
Anti-Mitogen-Activated Protein Kinase 14 antibodyAnti-Map Kinase 14 antibodyAnti-Mapk 14 antibodyAnti-Cytokine Suppressive Anti-Inflammatory Drug-Binding Protein antibodyAnti-Csaid-Binding Protein antibodyAnti-Csbp antibodyAn |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q16539 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human MAPK14 (NP_620581. 1). |
Short Description |
Rabbit polyclonal against MAPK14 |
Tissue specificity |
Brain, heart, placenta, pancreas and skeletal muscle. Expressed to a lesser extent in lung, liver and kidney. |
Cellular localization |
CytoplasmNucleus |
Molecular weight |
Calculated: 29kDa/34kDa/35kDa/41kDa. Observed: 38kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:100 |
Alternative names |
Anti-Mitogen-Activated Protein Kinase 14 antibodyAnti-Map Kinase 14 antibodyAnti-Mapk 14 antibodyAnti-Cytokine Suppressive Anti-Inflammatory Drug-Binding Protein antibodyAnti-Csaid-Binding Protein antibodyAnti-Csbp antibodyAnti-Map Kinase Mxi2 antibodyAnti-Max-Interacting Protein 2 antibodyAnti-Mitogen-Activated Protein Kinase P38 Alpha antibodyAnti-Map Kinase P38 Alpha antibodyAnti-Stress-Activated Protein Kinase 2a antibodyAnti-Sapk2a antibodyAnti-MAPK14 CSBP CSBP1 CSBP2 CSPB1 MXI2 SAPK2A antibody |
Protein name |
Mitogen-Activated Protein Kinase 14Map Kinase 14Mapk 14Cytokine Suppressive Anti-Inflammatory Drug-Binding ProteinCsaid-Binding ProteinCsbpMap Kinase Mxi2Max-Interacting Protein 2Mitogen-Activated Protein Kinase P38 AlphaMap Kinase P38 AlphaStress-Activated Protein Kinase 2aSapk2a |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.