Item no. |
STJ99613-200 |
Manufacturer |
St John's Laboratory
|
Amount |
200ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Mothers against decapentaplegic homolog 3 </br> MAD homolog 3 </br> Mad3 </br> Mothers against DPP homolog 3 </br> hMAD-3 </br> JV15-2 </br> SMAD family member 3 </br> SMAD 3 </br> Smad3 </br> hSMAD3 |
Similar products |
Mothers against decapentaplegic homolog 3 MAD homolog 3 Mad3 Mothers against DPP homolog 3 hMAD-3 JV15-2 SMAD family member 3 SMAD 3 Smad3 hSMAD3 |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Uniprot ID |
P84022 |
Storage |
Store at-20° C, and avoid repeat freeze-thaw cycles. |
Concentration |
1 mg/ml |
Description |
Rabbit polyclonal to Smad3. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Synthesized peptide derived from human Smad3. |
Short Description |
Rabbit polyclonal against Smad3 |
Cellular localization |
Cytoplasm Nucleus. Cytoplasmic and nuclear in the absence of TGF-beta. On TGF-beta stimulation, migrates to the nucleus when complexed with SMAD4. Through the action of the phosphatase PPM1A, released from the SMAD2/SMAD4 complex, and exported out of the nucleus by interaction with RANBP1. Co-localizes with LEMD3 at the nucleus inner membrane. MAPK-mediated phosphorylation appears to have no effect on nuclear import. PDPK1 prevents its nuclear translocation in response to TGF-beta. |
Molecular weight |
50 kDa |
Dilution range |
WB 1:500-2000ELISA 1:10000-20000 |
Alternative names |
Mothers against decapentaplegic homolog 3 MAD homolog 3 Mad3 Mothers against DPP homolog 3 hMAD-3 JV15-2 SMAD family member 3 SMAD 3 Smad3 hSMAD3 |
Protein name |
Mothers against decapentaplegic homolog 3 MAD homolog 3 Mad3 Mothers against DPP homolog 3 hMAD-3 JV15-2 SMAD family member 3 SMAD 3 Smad3 hSMAD3 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.