Item no. |
STJ95117-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF, ELISA, IHC-P |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Protein Kinase C Alpha Type antibody</br>Anti-Pkc-A antibody</br>Anti-Pkc-Alpha antibody</br>Anti-PRKCA PKCA PRKACA antibody |
Similar products |
Anti-Protein Kinase C Alpha Type antibodyAnti-Pkc-A antibodyAnti-Pkc-Alpha antibodyAnti-PRKCA PKCA PRKACA antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Uniprot ID |
P17252 |
Storage |
Store at-20° C, and avoid repeat freeze-thaw cycles. |
Concentration |
1 mg/ml |
Description |
PKC is a protein encoded by the PRKCA gene which is approximately 76, 7 kDa. PKC is localised to the cytoplasm and cell membrane. It is involved in RET signalling, DAG and IP3 signalling, the IL-2 Pathway, fMLP pathway and CDK-mediated phosphorylation and removal of Cdc6. It is a family of serine-and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. It plays a role in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. PKC is expressed in the liver, blood, nervous system, skin and pancreas. Mutations in the PRKCA gene may result in glioma and myotonic dystrophy. STJ95117 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of PKC protein. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Synthesized peptide derived from human PKC around the non-phosphorylation site of T497. |
Immunogen region |
600-680 aa |
Short Description |
Rabbit polyclonal against PKC |
Cellular localization |
CytoplasmCell MembranePeripheral Membrane ProteinMitochondrion MembraneNucleus |
Molecular weight |
85 kDa |
Dilution range |
WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000 |
Alternative names |
Anti-Protein Kinase C Alpha Type antibodyAnti-Pkc-A antibodyAnti-Pkc-Alpha antibodyAnti-PRKCA PKCA PRKACA antibody |
Protein name |
Protein Kinase C Alpha TypePkc-APkc-Alpha |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.