Anti-FoxO1A antibody

Polyclonal

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Q12778

1 mg/ml

2308

Synthesized peptide derived from human FoxO1A around the non-phosphorylation site of S329.

Rabbit polyclonal against FoxO1A

Cytoplasm
Nucleus
Shuttles Between The Cytoplasm And Nucleus
Largely Nuclear In Unstimulated Cells
In Osteoblasts
Colocalizes With Atf4 And Runx2 In The Nucleus (By Similarity)
Insulin-Induced Phosphorylation At Ser-256 By Pkb/Akt1 Leads
Via Stimulation Of Thr-24 Phosphorylation
To Binding Of 14-3-3 Proteins And Nuclear Export To The Cytoplasm Where It Is Degraded By The Ubiquitin-Proteosomal Pathway
Phosphorylation At Ser-249 By Cdk1 Disrupts Binding Of 14-3-3 Proteins And Promotes Nuclear Accumulation
Phosphorylation By Nlk Results In Nuclear Export
Translocates To The Nucleus Upon Oxidative Stress-Induced Phosphorylation At Ser-212 By Stk4/Mst1
Sgk1-Mediated Phosphorylation Also Results In Nuclear Translocation
Retained In The Nucleus Under Stress Stimuli Including Oxidative Stress
Nutrient Deprivation Or Nitric Oxide
Retained In The Nucleus On Methylation

WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000

Forkhead Box Protein O1
Forkhead Box Protein O1a
Forkhead In Rhabdomyosarcoma

FOXO1_HUMAN