Item no. |
STJ92463-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF, ELISA, IHC-P |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Cyclic Amp-Responsive Element-Binding Protein 1 antibody</br>Anti-Creb-1 antibody</br>Anti-Camp-Responsive Element-Binding Protein 1 antibody</br>Anti-CREB1 antibody |
Similar products |
Anti-Cyclic Amp-Responsive Element-Binding Protein 1 antibodyAnti-Creb-1 antibodyAnti-Camp-Responsive Element-Binding Protein 1 antibodyAnti-CREB1 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Uniprot ID |
P16220 |
Storage |
Store at-20° C, and avoid repeat freeze-thaw cycles. |
Concentration |
1 mg/ml |
Description |
CREB-1 is a protein encoded by the CREB1 gene which is approximately 36, 7 kDa. CREB-1 is localised to the nucleus and is involved in activated TLR4 signalling, DAG and IP3 signalling, RET signalling, post NMDA receptor activation events and GAB1 signalosome. This protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. It is involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. CREB-1 is expressed in the eye, liver, nervous system, blood and the adrenal gland. Mutations in the CREB1 gene result in Coffin-Lowry syndrome and Rubinstein-Taybi syndrome. STJ92463 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of CREB-1 protein. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Synthesized peptide derived from human CREB-1 around the non-phosphorylation site of S129. |
Immunogen region |
70-150 aa |
Short Description |
Rabbit polyclonal against CREB-1 |
Cellular localization |
Nucleus |
Molecular weight |
43 kDa |
Dilution range |
IF 1:50-200WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000 |
Alternative names |
Anti-Cyclic Amp-Responsive Element-Binding Protein 1 antibodyAnti-Creb-1 antibodyAnti-Camp-Responsive Element-Binding Protein 1 antibodyAnti-CREB1 antibody |
Protein name |
Cyclic Amp-Responsive Element-Binding Protein 1Creb-1Camp-Responsive Element-Binding Protein 1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.