Item no. |
STJ90781-200 |
Manufacturer |
St John's Laboratory
|
Amount |
200ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, ELISA, IHC-P |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Rac-Alpha Serine/Threonine-Protein Kinase antibody</br>Anti-Protein Kinase B antibody</br>Anti-Pkb antibody</br>Anti-Protein Kinase B Alpha antibody</br>Anti-Pkb Alpha antibody</br>Anti-Proto-Oncogene C-Akt antibody</br>Anti-Rac-Pk-Alpha antibody</br |
Similar products |
Anti-Rac-Alpha Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase B antibodyAnti-Pkb antibodyAnti-Protein Kinase B Alpha antibodyAnti-Pkb Alpha antibodyAnti-Proto-Oncogene C-Akt antibodyAnti-Rac-Pk-Alpha antibody
|
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Uniprot ID |
P31749 |
Storage |
Store at-20° C, and avoid repeat freeze-thaw cycles. |
Concentration |
1 mg/ml |
Description |
Rabbit polyclonal to Phospho-Akt (S124). |
Gene ID |
|
Gene symbol |
|
Immunogen |
Synthesized peptide derived from human Akt around the phosphorylation site of S124. |
Immunogen region |
60-140 aa |
Short Description |
Rabbit polyclonal against Phospho-Akt (S124) |
Tissue specificity |
Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages. |
Cellular localization |
CytoplasmNucleusCell MembraneNucleus After Activation By Integrin-Linked Protein Kinase 1 (Ilk1)Nuclear Translocation Is Enhanced By Interaction With Tcl1aPhosphorylation On Tyr-176 By Tnk2 Results In Its Localization To The Cell Membrane Where It Is Targeted For Further Phosphorylations On Thr-308 And Ser-473 Leading To Its Activation And The Activated Form Translocates To The NucleusColocalizes With Wdfy2 In Intracellular Vesicles |
Molecular weight |
55 kDa |
Dilution range |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000 |
Alternative names |
Anti-Rac-Alpha Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase B antibodyAnti-Pkb antibodyAnti-Protein Kinase B Alpha antibodyAnti-Pkb Alpha antibodyAnti-Proto-Oncogene C-Akt antibodyAnti-Rac-Pk-Alpha antibodyAnti-AKT1 PKB RAC antibody |
Protein name |
Rac-Alpha Serine/Threonine-Protein KinaseProtein Kinase BPkbProtein Kinase B AlphaPkb AlphaProto-Oncogene C-AktRac-Pk-Alpha |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.