Anti-SPTLC1 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

O15269

This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.

SPTLC1

Rabbit polyclonal against SPTLC1

Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein

WB 1:500-1:2000 IHC 1:50-1:200

Serine Palmitoyltransferase 1
Long Chain Base Biosynthesis Protein 1
Lcb 1
Serine-Palmitoyl-Coa Transferase 1
Spt 1
Spt1

SPTC1_HUMAN