Item no. |
STJ25351-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Transforming Protein Rhoa antibody</br>Anti-Rho Cdna Clone 12 antibody</br>Anti-H12 antibody</br>Anti-RHOA ARH12 ARHA RHO12 antibody |
Similar products |
Anti-Transforming Protein Rhoa antibodyAnti-Rho Cdna Clone 12 antibodyAnti-H12 antibodyAnti-RHOA ARH12 ARHA RHO12 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P61586 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. |
Gene ID |
|
Gene symbol |
|
Immunogen |
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RhoA (NP_001655. 1). |
Short Description |
Rabbit polyclonal against RHOA |
Cellular localization |
Cell MembraneLipid-AnchorCytoplasmic SideCytoplasmCytoskeletonCleavage FurrowCell CortexMidbodyCell ProjectionLamellipodiumDendriteLocalized To Cell-Cell Contacts In Calcium-Treated KeratinocytesTranslocates To The Equatorial Region Before Furrow Formation In A Ect2-Dependent MannerLocalizes To The Equatorial Cell Cortex (At The Site Of The Presumptive Furrow) In Early Anaphase In An Activated Form And In A Myosin-And Actin-Independent Manner |
Molecular weight |
Calculated: 21kDa. Observed: 22kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Transforming Protein Rhoa antibodyAnti-Rho Cdna Clone 12 antibodyAnti-H12 antibodyAnti-RHOA ARH12 ARHA RHO12 antibody |
Protein name |
Transforming Protein RhoaRho Cdna Clone 12H12 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.