Item no. |
STJ25176-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Proteasome Subunit Beta Type-5 antibody</br>Anti-Macropain Epsilon Chain antibody</br>Anti-Multicatalytic Endopeptidase Complex Epsilon Chain antibody</br>Anti-Proteasome Chain 6 antibody</br>Anti-Proteasome Epsilon Chain antibody</br>Anti-Proteasome |
Similar products |
Anti-Proteasome Subunit Beta Type-5 antibodyAnti-Macropain Epsilon Chain antibodyAnti-Multicatalytic Endopeptidase Complex Epsilon Chain antibodyAnti-Proteasome Chain 6 antibodyAnti-Proteasome Epsilon Chain antibodyAnti-Proteasome |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P28074 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-263 of human PSMB5 (NP_002788. 1). |
Short Description |
Rabbit polyclonal against PSMB5 |
Cellular localization |
CytoplasmNucleus |
Molecular weight |
Calculated: 17kDa/21kDa/28kDa. Observed: 21kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 |
Alternative names |
Anti-Proteasome Subunit Beta Type-5 antibodyAnti-Macropain Epsilon Chain antibodyAnti-Multicatalytic Endopeptidase Complex Epsilon Chain antibodyAnti-Proteasome Chain 6 antibodyAnti-Proteasome Epsilon Chain antibodyAnti-Proteasome Subunit Mb1 antibodyAnti-Proteasome Subunit X antibodyAnti-PSMB5 LMPX MB1 X antibody |
Protein name |
Proteasome Subunit Beta Type-5Macropain Epsilon ChainMulticatalytic Endopeptidase Complex Epsilon ChainProteasome Chain 6Proteasome Epsilon ChainProteasome Subunit Mb1Proteasome Subunit X |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.