Anti-PLS3 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P13797

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc. ). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.

PLS3

Rabbit polyclonal against PLS3

Cytoplasm

WB 1:200-1:2000 IHC 1:50-1:100

Plastin-3
T-Plastin

PLST_HUMAN