Item no. |
STJ25021-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Urokinase-Type Plasminogen Activator antibody</br>Anti-U-Plasminogen Activator antibody</br>Anti-Upa Cleaved Into-Urokinase-Type Plasminogen Activator Long Chain A-Urokinase-Type Plasminogen Activator Short Chain A-Urokinase-Type Plasminogen Activato |
Similar products |
Anti-Urokinase-Type Plasminogen Activator antibodyAnti-U-Plasminogen Activator antibodyAnti-Upa Cleaved Into-Urokinase-Type Plasminogen Activator Long Chain A-Urokinase-Type Plasminogen Activator Short Chain A-Urokinase-Type Plasminogen Activato |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P00749 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 20-180 of human PLAU (NP_002649. 1). |
Short Description |
Rabbit polyclonal against PLAU |
Tissue specificity |
Expressed in the prostate gland and prostate cancers. |
Cellular localization |
Secreted |
Molecular weight |
Calculated: 46kDa/48kDa. Observed: 49kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Urokinase-Type Plasminogen Activator antibodyAnti-U-Plasminogen Activator antibodyAnti-Upa Cleaved Into-Urokinase-Type Plasminogen Activator Long Chain A-Urokinase-Type Plasminogen Activator Short Chain A-Urokinase-Type Plasminogen Activator Chain B antibodyAnti-PLAU antibody |
Protein name |
Urokinase-Type Plasminogen ActivatorU-Plasminogen ActivatorUpa Cleaved Into-Urokinase-Type Plasminogen Activator Long Chain A-Urokinase-Type Plasminogen Activator Short Chain A-Urokinase-Type Plasminogen Activator Chain B |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.