Anti-DDB2 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q92466

This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

DDB2

Rabbit polyclonal against DDB2

Nucleus
Accumulates At Sites Of Dna Damage Following Uv Irradiation

WB 1:500-1:2000 IF 1:50-1:200

Dna Damage-Binding Protein 2
Ddb P48 Subunit
Ddbb
Damage-Specific Dna-Binding Protein 2
Uv-Damaged Dna-Binding Protein 2
Uv-Ddb 2

DDB2_HUMAN