Item no. |
STJ116926-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
IF, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Segment Polarity Protein Dishevelled Homolog Dvl-2 antibody</br>Anti-Dishevelled-2 antibody</br>Anti-Dsh Homolog 2 antibody</br>Anti-DVL2 antibody |
Similar products |
Anti-Segment Polarity Protein Dishevelled Homolog Dvl-2 antibodyAnti-Dishevelled-2 antibodyAnti-Dsh Homolog 2 antibodyAnti-DVL2 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
O14641 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human DVL2 (NP_004413. 1). |
Short Description |
Rabbit polyclonal against DVL2 |
Cellular localization |
Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytosolCytoplasmic VesicleNucleusLocalizes At The Cell Membrane Upon Interaction With Frizzled Family Members And Promotes Their InternalizationLocalizes To Cytoplasmic PunctaInteraction With Foxk1 And Foxk2 Induces Nuclear Translocation |
Molecular weight |
Calculated: 78kDa. Observed: |
Dilution range |
IHC 1:50-1:200 IF 1:50-1:200 |
Alternative names |
Anti-Segment Polarity Protein Dishevelled Homolog Dvl-2 antibodyAnti-Dishevelled-2 antibodyAnti-Dsh Homolog 2 antibodyAnti-DVL2 antibody |
Protein name |
Segment Polarity Protein Dishevelled Homolog Dvl-2Dishevelled-2Dsh Homolog 2 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.