Anti-FAT1 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q14517

This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.

FAT1

Rabbit polyclonal against FAT1

Cell Membrane
Single-Pass Type I Membrane Protein
Nucleus
Cytoplasm
Perinuclear Region

WB 1:500-1:2000

Protocadherin Fat 1
Cadherin Family Member 7
Cadherin-Related Tumor Suppressor Homolog
Protein Fat Homolog Cleaved Into-Protocadherin Fat 1-Nuclear Form

FAT1_HUMAN