Item no. |
STJ116077-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 5.1 |
32160702 |
ECLASS 6.1 |
32160702 |
ECLASS 8.0 |
32160702 |
ECLASS 9.0 |
32160702 |
ECLASS 10.0.1 |
32160702 |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Butyrophilin-Like Protein 2 antibody</br>Anti-Btl-Ii antibody</br>Anti-BTNL2 antibody |
Similar products |
Anti-Butyrophilin-Like Protein 2 antibodyAnti-Btl-Ii antibodyAnti-BTNL2 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q9UIR0 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 246-455 of human BTNL2 (NP_062548. 1). |
Short Description |
Rabbit polyclonal against BTNL2 |
Tissue specificity |
Expressed in brain, heart, kidney, liver, pancreas, ovary, leukocyte, small intestine, testis and thymus. |
Cellular localization |
MembraneSingle-Pass Type Ii Membrane ProteinIsoform 2 Is Present In The NuclearVesicle And Plasma MembranesIsoform 3 Is Found In Cytoplasmic Vesicle Structures And Is Not Membrane Bound |
Molecular weight |
Calculated: 19kDa/27kDa/28kDa/30kDa/43kDa/50kDa. |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Butyrophilin-Like Protein 2 antibodyAnti-Btl-Ii antibodyAnti-BTNL2 antibody |
Protein name |
Butyrophilin-Like Protein 2Btl-Ii |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.