Anti-BTNL2 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q9UIR0

This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer.

BTNL2

Rabbit polyclonal against BTNL2

Membrane
Single-Pass Type Ii Membrane Protein
Isoform 2 Is Present In The Nuclear
Vesicle And Plasma Membranes
Isoform 3 Is Found In Cytoplasmic Vesicle Structures And Is Not Membrane Bound

WB 1:500-1:2000

Butyrophilin-Like Protein 2
Btl-Ii

BTNL2_HUMAN