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Anti-HLA-DOB antibody

Anti-HLA-DOB antibody

Item no.	STJ114153-100
Manufacturer	St John's Laboratory
Amount	100ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Hla Class Ii Histocompatibility Antigen-Do Beta Chain antibody</br>Anti-Mhc Class Ii Antigen Dob antibody</br>Anti-HLA-DOB antibody
Similar products	Anti-Hla Class Ii Histocompatibility Antigen-Do Beta Chain antibody Anti-Mhc Class Ii Antigen Dob antibody Anti-HLA-DOB antibody
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P13765
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
Gene ID	3112
Gene symbol	HLA-DOB
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 27-224 of human HLA-DOB (NP_002111. 1).
Short Description	Rabbit polyclonal against HLA-DOB
Cellular localization	Endosome Membrane Single-Pass Type I Membrane Protein Lysosome Membrane Complexes With Hla-Dm Molecule During Intracellular Transport And In Endosomal/Lysosomal Compartments Heterotetramerization Is Necessary To Exit The Er
Molecular weight	Calculated: 30kDa. Observed: 36kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Hla Class Ii Histocompatibility Antigen-Do Beta Chain antibody Anti-Mhc Class Ii Antigen Dob antibody Anti-HLA-DOB antibody
Protein name	Hla Class Ii Histocompatibility Antigen-Do Beta Chain Mhc Class Ii Antigen Dob
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	DOB_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 9/27/2024

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