Item no. |
STJ113310-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Protein-Arginine Deiminase Type-2 antibody</br>Anti-Pad-H19 antibody</br>Anti-Peptidylarginine Deiminase Ii antibody</br>Anti-Protein-Arginine Deiminase Type Ii antibody</br>Anti-PADI2 KIAA0994 PAD2 PDI2 antibody |
Similar products |
Anti-Protein-Arginine Deiminase Type-2 antibodyAnti-Pad-H19 antibodyAnti-Peptidylarginine Deiminase Ii antibodyAnti-Protein-Arginine Deiminase Type Ii antibodyAnti-PADI2 KIAA0994 PAD2 PDI2 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q9Y2J8 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 26-210 of human PADI2 (NP_031391. 2). |
Short Description |
Rabbit polyclonal against PADI2 |
Tissue specificity |
Detected in keratinocytes in epidermis (at protein level). |
Cellular localization |
Cytoplasm |
Molecular weight |
Calculated: 49kDa/75kDa. Observed: 75kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Protein-Arginine Deiminase Type-2 antibodyAnti-Pad-H19 antibodyAnti-Peptidylarginine Deiminase Ii antibodyAnti-Protein-Arginine Deiminase Type Ii antibodyAnti-PADI2 KIAA0994 PAD2 PDI2 antibody |
Protein name |
Protein-Arginine Deiminase Type-2Pad-H19Peptidylarginine Deiminase IiProtein-Arginine Deiminase Type Ii |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.