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Anti-LGR5 antibody

Anti-LGR5 antibody

Item no.	STJ112563-50
Manufacturer	St John's Laboratory
Amount	50ul
Category	Metabolism Diabetes Glucose Homeostasis Antibodies Obesity Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 5 antibody</br>Anti-G-Protein Coupled Receptor 49 antibody</br>Anti-G-Protein Coupled Receptor 67 antibody</br>Anti-G-Protein Coupled Receptor Hg38 antibody</br>Anti-LGR5 GPR49 GPR67 antibody
Similar products	Anti-Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 5 antibody Anti-G-Protein Coupled Receptor 49 antibody Anti-G-Protein Coupled Receptor 67 antibody Anti-G-Protein Coupled Receptor Hg38 antibody Anti-LGR5 GPR49 GPR67 antibody
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	O75473
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
Gene ID	8549
Gene symbol	LGR5
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 824-907 of human LGR5 (NP_003658. 1).
Short Description	Rabbit polyclonal against LGR5
Tissue specificity	Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers of the ovary, colon and liver.
Cellular localization	Cell Membrane Multi-Pass Membrane Protein Golgi Apparatus Trans-Golgi Network Membrane Rapidly And Constitutively Internalized To The Trans-Golgi Network At Steady State Internalization To The Trans-Golgi Network May Be The Result Of Phosphorylation At Ser-861 And Ser-864 However The Phosphorylation Event Has Not Been Proven
Molecular weight	Calculated: 92kDa/97kDa/99kDa. Observed: 105kDa
Dilution range	WB 1:1000-1:2000
Alternative names	Anti-Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 5 antibody Anti-G-Protein Coupled Receptor 49 antibody Anti-G-Protein Coupled Receptor 67 antibody Anti-G-Protein Coupled Receptor Hg38 antibody Anti-LGR5 GPR49 GPR67 antibody
Protein name	Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 5 G-Protein Coupled Receptor 49 G-Protein Coupled Receptor 67 G-Protein Coupled Receptor Hg38
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	LGR5_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 9/27/2024

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