Item no. |
STJ111865-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Protein Jumonji antibody</br>Anti-Jumonji/Arid Domain-Containing Protein 2 antibody</br>Anti-JARID2 JMJ antibody |
Similar products |
Anti-Protein Jumonji antibodyAnti-Jumonji/Arid Domain-Containing Protein 2 antibodyAnti-JARID2 JMJ antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q92833 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a Jumonji-and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1027-1246 of human JARID2 (NP_004964. 2). |
Short Description |
Rabbit polyclonal against JARID2 |
Tissue specificity |
During embryogenesis, predominantly expressed in neurons and particularly in dorsal root ganglion cells. |
Cellular localization |
NucleusColocalizes With The Prc2 Complex On Chromatin |
Molecular weight |
Calculated: 106kDa/119kDa/138kDa. Observed: 160kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Protein Jumonji antibodyAnti-Jumonji/Arid Domain-Containing Protein 2 antibodyAnti-JARID2 JMJ antibody |
Protein name |
Protein JumonjiJumonji/Arid Domain-Containing Protein 2 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.