Anti-WNT1 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P04628

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.

WNT1

Rabbit polyclonal against WNT1

Calculated: 40kDa. Observed: 49kDa

Anti-Proto-Oncogene Wnt-1 antibody
Anti-Proto-Oncogene Int-1 Homolog antibody
Anti-WNT1 INT1 antibody

FOR RESEARCH USE ONLY (RUO).