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Anti-HMGCL antibody

Anti-HMGCL antibody

Item no.	STJ110355-50
Manufacturer	St John's Laboratory
Amount	50ul
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Hydroxymethylglutaryl-Coa Lyase-Mitochondrial antibody</br>Anti-Hl antibody</br>Anti-Hmg-Coa Lyase antibody</br>Anti-3-Hydroxy-3-Methylglutarate-Coa Lyase antibody</br>Anti-HMGCL antibody
Similar products	Anti-Hydroxymethylglutaryl-Coa Lyase-Mitochondrial antibody Anti-Hl antibody Anti-Hmg-Coa Lyase antibody Anti-3-Hydroxy-3-Methylglutarate-Coa Lyase antibody Anti-HMGCL antibody
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P35914
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID	3155
Gene symbol	HMGCL
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human HMGCL (NP_000182. 2).
Short Description	Rabbit polyclonal against HMGCL
Tissue specificity	Highest expression in liver. Expressed in pancreas, kidney, intestine, testis, fibroblasts and lymphoblasts. Very low expression in brain and skeletal muscle. The relative expression of isoform 2 (at mRNA level) is highest in heart (30%), skeletal muscle (22%), and brain (14%).
Cellular localization	Mitochondrion Matrix Peroxisome Unprocessed Form Is Peroxisomal
Molecular weight	Calculated: 20kDa/26kDa/34kDa. Observed: 30kDa
Dilution range	WB 1:500-1:2000 IHC 1:50-1:200
Alternative names	Anti-Hydroxymethylglutaryl-Coa Lyase-Mitochondrial antibody Anti-Hl antibody Anti-Hmg-Coa Lyase antibody Anti-3-Hydroxy-3-Methylglutarate-Coa Lyase antibody Anti-HMGCL antibody
Protein name	Hydroxymethylglutaryl-Coa Lyase-Mitochondrial Hl Hmg-Coa Lyase 3-Hydroxy-3-Methylglutarate-Coa Lyase
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	HMGCL_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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