Item no. |
STJ110334-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Pyruvate Dehydrogenase antibody</br>Anti-Acetyl-Transferring Kinase Isozyme 3-Mitochondrial antibody</br>Anti-Pyruvate Dehydrogenase Kinase Isoform 3 antibody</br>Anti-PDK3 PDHK3 antibody |
Similar products |
Anti-Pyruvate Dehydrogenase antibodyAnti-Acetyl-Transferring Kinase Isozyme 3-Mitochondrial antibodyAnti-Pyruvate Dehydrogenase Kinase Isoform 3 antibodyAnti-PDK3 PDHK3 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q15120 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 137-406 of human PDK3 (NP_005382. 1). |
Short Description |
Rabbit polyclonal against PDK3 |
Tissue specificity |
Expressed in heart, skeletal muscle, spinal cord, as well as fetal and adult brain. |
Cellular localization |
Mitochondrion Matrix |
Molecular weight |
Calculated: 46kDa/48kDa. Observed: 47kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:100 |
Alternative names |
Anti-Pyruvate Dehydrogenase antibodyAnti-Acetyl-Transferring Kinase Isozyme 3-Mitochondrial antibodyAnti-Pyruvate Dehydrogenase Kinase Isoform 3 antibodyAnti-PDK3 PDHK3 antibody |
Protein name |
Pyruvate DehydrogenaseAcetyl-Transferring Kinase Isozyme 3-MitochondrialPyruvate Dehydrogenase Kinase Isoform 3 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.