Item no. |
STJ110163-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Vacuolar Protein Sorting-Associated Protein 37a antibody</br>Anti-Hvps37a antibody</br>Anti-Escrt-I Complex Subunit Vps37a antibody</br>Anti-Hepatocellular Carcinoma-Related Protein 1 antibody</br>Anti-VPS37A HCRP1 antibody |
Similar products |
Anti-Vacuolar Protein Sorting-Associated Protein 37a antibodyAnti-Hvps37a antibodyAnti-Escrt-I Complex Subunit Vps37a antibodyAnti-Hepatocellular Carcinoma-Related Protein 1 antibodyAnti-VPS37A HCRP1 antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q8NEZ2 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 224-397 of human VPS37A (NP_689628. 2). |
Short Description |
Rabbit polyclonal against VPS37A |
Tissue specificity |
Widely expressed. Examined tissues include heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. More abundant in liver. Strongly decreased or undetected in hepatomas. |
Cellular localization |
Late Endosome MembranePeripheral Membrane ProteinNucleus |
Molecular weight |
Calculated: 20kDa/41kDa/44kDa. Observed: 44kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 |
Alternative names |
Anti-Vacuolar Protein Sorting-Associated Protein 37a antibodyAnti-Hvps37a antibodyAnti-Escrt-I Complex Subunit Vps37a antibodyAnti-Hepatocellular Carcinoma-Related Protein 1 antibodyAnti-VPS37A HCRP1 antibody |
Protein name |
Vacuolar Protein Sorting-Associated Protein 37aHvps37aEscrt-I Complex Subunit Vps37aHepatocellular Carcinoma-Related Protein 1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.