Item no. |
STJ110154-50 |
Manufacturer |
St John's Laboratory
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Chrna7-Fam7a Fusion Protein antibody</br>Anti-Chrna7-Dr1 antibody</br>Anti-D-10 antibody</br>Anti-CHRFAM7A antibody |
Similar products |
Anti-Chrna7-Fam7a Fusion Protein antibodyAnti-Chrna7-Dr1 antibodyAnti-D-10 antibodyAnti-CHRFAM7A antibody |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q494W8 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human CHRFAM7A (NP_647536. 1). |
Short Description |
Rabbit polyclonal against CHRFAM7A |
Tissue specificity |
Expressed in hippocampus. |
Cellular localization |
MembraneMulti-Pass Membrane Protein |
Molecular weight |
Calculated: 46kDa. Observed: 46kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 |
Alternative names |
Anti-Chrna7-Fam7a Fusion Protein antibodyAnti-Chrna7-Dr1 antibodyAnti-D-10 antibodyAnti-CHRFAM7A antibody |
Protein name |
Chrna7-Fam7a Fusion ProteinChrna7-Dr1D-10 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.