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Anti-PLCG1 antibody

Anti-PLCG1 antibody

Item no.	STJ110022-50
Manufacturer	St John's Laboratory
Amount	50ul
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Western Blot Cardiovascular Research Thrombosis & Hemostasis Enzymes Other Fatty Acid Enzymes Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-1-Phosphatidylinositol 4-5-Bisphosphate Phosphodiesterase Gamma-1 antibody</br>Anti-Plc-148 antibody</br>Anti-Phosphoinositide Phospholipase C-Gamma-1 antibody</br>Anti-Phospholipase C-Ii antibody</br>Anti-Plc-Ii antibody</br>Anti-Phospholipase C-Gam
Similar products	Anti-1-Phosphatidylinositol 4-5-Bisphosphate Phosphodiesterase Gamma-1 antibody Anti-Plc-148 antibody Anti-Phosphoinositide Phospholipase C-Gamma-1 antibody Anti-Phospholipase C-Ii antibody Anti-Plc-Ii antibody Anti-Phospholipase C-Gam
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P19174
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene catalyzes the formation of inositol 1, 4, 5-trisphosphate and diacylglycerol from phosphatidylinositol 4, 5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID	5335
Gene symbol	PLCG1
Immunogen	A synthetic peptide of human PLCG1
Short Description	Rabbit polyclonal against PLCG1
Cellular localization	Cell Projection Lamellipodium Ruffle Rapidly Redistributed To Ruffles And Lamellipodia Structures In Response To Epidermal Growth Factor (Egf) Treatment
Molecular weight	Calculated: 148kDa. Observed: 160kDa
Dilution range	WB 1:500-1:2000 IHC 1:50-1:200
Alternative names	Anti-1-Phosphatidylinositol 4-5-Bisphosphate Phosphodiesterase Gamma-1 antibody Anti-Plc-148 antibody Anti-Phosphoinositide Phospholipase C-Gamma-1 antibody Anti-Phospholipase C-Ii antibody Anti-Plc-Ii antibody Anti-Phospholipase C-Gamma-1 antibody Anti-Plc-Gamma-1 antibody Anti-PLCG1 PLC1 antibody
Protein name	1-Phosphatidylinositol 4-5-Bisphosphate Phosphodiesterase Gamma-1 Plc-148 Phosphoinositide Phospholipase C-Gamma-1 Phospholipase C-Ii Plc-Ii Phospholipase C-Gamma-1 Plc-Gamma-1
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	PLCG1_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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