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Anti-EGLN1 antibody

Anti-EGLN1 antibody

Item no.	STJ23492-50
Manufacturer	St John's Laboratory
Amount	50ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human, Simian
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Purification	Affinity purification
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-426 of human EGLN1 (NP_071334. 1).
Short Description	Rabbit polyclonal against EGLN1
Dilution range	WB 1:500-1:2000
Note	FOR RESEARCH USE ONLY (RUO).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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