Anti-SNAI 1 antibody

Unconjugated

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Store at-20° C, and avoid repeat freeze-thaw cycles.

SNAI 1 is a protein encoded by the SNAI1 gene which is approximately 29 kDa. SNAI 1 is localised to the cytoplasm and nucleus. It is involved in the development HGF signalling pathway and embryonic and induced pluripotent stem cell differentiation pathways and lineage-specific markers. It plays a role in the induction of the epithelial to mesenchymal transition, formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. It binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A, causes a decrease in dimethylated H3K4 levels and represses transcription. SNAI 1 is expressed in a variety of tissues with the highest expression in kidney. Mutations in the SNAI1 gene may result in cercarial dermatitis and fasciolopsiasis. STJ95716 was affinity purified. This poly clonal antibody binds SNAI 1.

SNAI1

190-270 aa

Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines.

29 kDa

Anti-Zinc Finger Protein Snai1 antibody
Anti-Protein Snail Homolog 1 antibody
Anti-Protein Sna antibody
Anti-SNAI1 SNAH antibody

FOR RESEARCH USE ONLY (RUO).