Manufacturer |
St John's Laboratory
|
Category |
|
Type |
Antibody Monoclonal |
Specific against |
Human, Mouse, Rat, Monkey |
Clone |
2E9-E8-E9 |
Isotype |
IgG2b |
Applications |
WB, IP |
Amount |
50ul |
Host |
Mouse |
Item no. |
STJ99160-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
42030590 |
Available |
|
Alias |
Switch-associated protein 70 </br> SWAP-70 |
Clonality |
Monoclonal |
Conjugation |
Unconjugated |
Formulation |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Uniprot ID |
Q9UH65 |
Storage |
Store at-20° C, and avoid repeat freeze-thaw cycles. |
Concentration |
1 mg/ml |
Description |
Mouse monoclonal to SWAP70. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Purified recombinant human SWAP70 protein fragments expressed in E.coli. |
Short Description |
Mouse monoclonal against SWAP70 |
Tissue specificity |
Expressed only in mature B-cells including those associated with mucosa-associated tissue and bronchus-associated tissue. Widely expressed. Abundant in spleen, and fairly abundant in kidney, lung and liver. Also found in monocytes and macrophages. |
Cellular localization |
Cytoplasm Cell membrane. Nucleus Cell projection, lamellipodium Cytoplasm, cytoskeleton. In resting B-cells it is localized mainly in the cytoplasm and upon cell activation it is recruited to the plasma membrane and then translocates to the nucleus. In activated, class-switching B-cells it is associated with membrane IgG but not IgM. Localized to loose actin filament arrays located behind actively extending lamellipodia. |
Molecular weight |
70kDa |
Dilution range |
WB 1:1000 |
Alternative names |
Switch-associated protein 70 SWAP-70 |
Protein name |
Switch-associated protein 70 SWAP-70 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.