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Human NRG1-alpha Protein (EGF Domain, Fc Tag)

Human NRG1-alpha Protein (EGF Domain, Fc Tag)

Item no.	13499-H01H-50
Manufacturer	Sino Biological
Amount	50 ug
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling By Cell Type Carcinoma Melanoma Peptides & Proteins Recombinant Proteins Adenocarcinoma Neuronal Cell Markers
Type	Proteins
Format	Human Cell
Specific against	Human
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, Neuregulin 1, NRG1-IT2, SMDF
Similar products	NRG1
Available
Molecule	NRG1
Synonym	ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, Neuregulin 1, NRG1-IT2, SMDF
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the human NRG1 isoform alpha (Q02297-1) EGF-like domain (Ser 177-Lys 241) was fused with the Fc region of human IgG1 at the N-terminus.
Expressed Host	Human Cells
Purity	> 97 % as determined by SDS-PAGE
Bio-Activity	1. Measured by its ability to biotinylated Human ErbB4-Fc (cat:10363-H03H) in functional Elisa. 2. Measured by its ability to biotinylated Rhesus ErbB3 (Cat:90043-K02H) in functional Elisa.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Glu
Molecule Mass	The recombinant human NRG1(177-241)/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 326 amino acids and has a calculated molecular mass of 35.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of the protein is approximately 38 kDa.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	Q02297-1
Amino acid sequence	Ser177-Lys241
TAG	N-human IgG1-Fc

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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