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Human TROP2 / TACSTD2 Protein (His & Fc Tag)

Human TROP2 / TACSTD2 Protein (His & Fc Tag)

Item no.	10428-H03H-200
Manufacturer	Sino Biological
Amount	200 ug
Category	Oncology By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins
Type	Proteins
Format	Human Cell
Specific against	Human (Homo sapiens)
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TACD2, TROP-2, TROP2
Similar products	TACSTD2
Available
Molecule	TACSTD2
Synonym	EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TACD2, TROP-2, TROP2
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the extracellular domain (Met 1-Thr 274) of human TROP2 (NP_002344.2) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Expressed Host	Human Cells
Purity	> 98 % as determined by SDS-PAGE
Bio-Activity	Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells . When cells are added to TROP2-coated plates (10 ug/ml, 100 ul/well), approximately 90%-100% will adhere specifically .
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	His 27
Molecule Mass	The recombinant human TROP2/Fc is a disulfide-linked homodimer. The reduced monomer consists of 495 amino acids and has a predicted molecular mass of 55.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhTROP2/Fc monomer is approximately 65-75 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_002344.2
Amino acid sequence	Met1-Thr274
TAG	C-human IgG1-Fc & His

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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