Item no. |
10359-H02H-50 |
Manufacturer |
Sino Biological
|
Amount |
50ug |
Category |
|
Type |
Proteins |
Format |
Human Cell |
Specific against |
Human |
Host |
Human |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
IFN-alpha-REC, IFN-R, IFNABR, IFNARB |
Similar products |
IFNAR2 |
Available |
|
Molecule |
IFNAR2 |
Synonym |
IFN-alpha-REC, IFN-R, IFNABR, IFNARB |
Storage |
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Protein Construction |
A DNA sequence encoding the extracellular domain of human IFNAR2 isoform a (NP_997468.1) (Met 1-Lys 243) was fused with the Fc region of human IgG1 at the C-terminus. |
Expressed Host |
Human Cells |
Purity |
> 90 % as determined by SDS-PAGE |
Bio-Activity |
Measured by its ability to inhibit rh IFNbeta mediated protection of WISH Human amnion cells infected with vesicular stomatitis virus (VSV) to viral lysis. The EC50 for this effect is typically 0.01-0.05 ug/mL. |
Endotoxin |
< 1.0 EU per ug of the protein as determined by the LAL method |
Predicted N Terminal |
Ile 27 |
Molecule Mass |
The recombinant human IFNAR2/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 458 amino acids and predicts a molecular mass of 51.8 kDa. As a result of glycosylation, the apparent molecular mass of rh IFNAR2/Fc monomer is approximately 65-75 kDa in SDS-PAGE under reducing conditions. |
Formulation |
Lyophilized from sterile PBS, pH 7.4 |
Accession |
NP_997468.1 |
Amino acid sequence |
Met1-Lys243 |
TAG |
C-human IgG1-Fc |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.