ISRIB

Item no.	RPE-N-1539-2
Manufacturer	rPeptide
Amount	25 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Format	Powder
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Territory	This product is only available for customers from Austria or Switzerland!
Manufacturers Category	Neurodegenerative Related Compounds
Storage	-20°C
Shipping	Ambient
Description (Long)	Integrated stress response inhibitor. Potently reverses the effects of initiation factor 2α (eIF2α) phosphorylation, IC50=5 nM1. Enhances spatial and fear-associated learning in mice and enhances cognitive function1, 2. Mechanism of action involves activation of eiF2β3. Suppresses ER stress-induced inflammatory gene expression4. Potently attenuates amyloid β-induced neuronal cell death (12.5-25 nM) with no effect on amyloid β production5. Reverses hippocampal-dependent cognitive deficits induced by traumatic brain injury in two different injury mouse models6.
Physical State	White Powder

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 25 mg

available

Delivery expected until 10/4/2024

Express Delivery: Save 11 days

Compare

Add to wishlist

Recommend by mail