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Flt-3 Ligand

Flt-3 Ligand

Item no.	RLT-100-026S
Manufacturer	ReliaTech
Amount	2ug
Category	Oncology By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	FLT3, FLK2, STK1, CD135, FLK-2
Available
NCBI Gene ID	2323
Uniprot	P49771
Biological Activity	The ED50 range=0.5-1.0 ng/ml corresponding to a specific activity of 1-2MUnits/mg, calculated by the dose-dependant stimulation of the proliferation of human OCMI-AML5 cells.
Description	Flt3-ligand (flk2-ligand) stimulates the proliferation and colony formation of certain BM precursor cells including CD34+ cells. Flt3-ligand produced in E. coli is a soluble non-glycosylated 17.6 kDa polypeptide containing 155 amino acid residues which comprises the extracellular domain of the transmembrane flt3-ligand protein.
Length [aa]	155
Molecular Weight	17.6 kDa
mRNA RefSeq	NM_001459.3
Protein RefSeq	NP_001450.2
Protein Sequence	TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA
Purity Confirmation	> 95% by SDS-PAGE and RP-HPLC
Synonyms	FLT3; FLK2; STK1; CD135; FLK-2
Uniprot ID	P49771

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Amount: 2ug

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Delivery expected until 8/16/2024