BCA-1

Item no.	RLT-100-003S
Manufacturer	ReliaTech
Amount	5ug
Category	Oncology Neuroscience Neuroinflammation By Cell Type Hematology Lymphoma Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	CXCL13, BLC, BCA1, ANGIE, BCA-1, BLR1L, ANGIE2, SCYB13
Available
NCBI Gene ID	10563
Uniprot	O43927
Biological Activity	The biological activity of human BCA-1 was determined by chemotaxis assay using human B cells. Significant chemotaxis was achieved at a concentration range of 1.0-10 ng/ml.
Description	BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Human BCA-1 is a 10.3 kDa protein containing 87 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	87
Molecular Weight	10.3 kDa
mRNA RefSeq	NM_006419.2
Protein RefSeq	NP_006410.1
Protein Sequence	VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	CXCL13; BLC; BCA1; ANGIE; BCA-1; BLR1L; ANGIE2; SCYB13
Uniprot ID	O43927

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Delivery expected until 8/16/2024