IL-5

Item no.	RLT-M10-046
Manufacturer	ReliaTech
Amount	25ug
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	Il5, Il-5, B-cell growth factor II Short name=BCGF-II Cytotoxic T-lymphocyte inducer Eosinophil differentiation factor T-cell replacing factor
Available
NCBI Gene ID	16191
Uniprot	P04401
Biological Activity	The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells and is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg.
Description	IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	113
Molecular Weight	26.2 kDa
mRNA RefSeq	NM_010558.1
Protein RefSeq	NP_034688.1
Protein Sequence	MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	Il5; Il-5; B-cell growth factor II Short name=BCGF-II Cytotoxic T-lymphocyte inducer Eosinophil differentiation factor T-cell replacing factor
Uniprot ID	P04401

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