IL-4

Item no.	RLT-M10-016
Manufacturer	ReliaTech
Amount	20ug
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human, Mouse, Rat, Porcine
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	Il4, Il-4, BSF-1
Available
NCBI Gene ID	16189
Uniprot	P07750
Biological Activity	The ED50 was determined by the dose-dependent proliferation of murine HT-2 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg.
Description	Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	120
Molecular Weight	13.5 kDa
mRNA RefSeq	NM_021283
Protein RefSeq	NP_067258
Protein Sequence	MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	Il4; Il-4; BSF-1
Uniprot ID	P07750

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Delivery expected until 8/16/2024