CNTF

Item no.	RLT-100-007
Manufacturer	ReliaTech
Amount	20ug
Category	Neuroscience Metabolism Diabetes Glucose Homeostasis Regulation of Appetite Molecular Targets for Neuroscience Neural Signaling Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human, Mouse, Rat, Hamster, Frog
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	CNTF, HCNTF
Available
NCBI Gene ID	1270
Uniprot	P26441
Biological Activity	Determined by its ability to stimulate proliferation of human TF-1 cells using an ED50 concentration range of 50-150 ng/ml.
Buffer	5 mM Sodium Phosphate, pH 7.5 + 75 mM NaCl
Description	CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity. Recombinant human CNTF is synthesized as a 199 amino acid polypeptide (22.7 kDa) lacking a hydrophobic N-terminal signal for secretion
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	199
Molecular Weight	22.7 kDa
mRNA RefSeq	NM_000614
Protein RefSeq	NP_000605
Protein Sequence	MAFTEHSPLT PHRRDLCSRS IWLARKLRSD LTALTESYVK HQGLNKNINL DSADGMPVAS TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG SHYIANNKKM
Purity Confirmation	98% by SDS-PAGE & HPLC analyses
Synonyms	CNTF; HCNTF
Uniprot ID	P26441

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Amount: 20ug

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Delivery expected until 8/16/2024