NT-3

Item no.	RLT-100-086S
Manufacturer	ReliaTech
Amount	2ug
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human, Mouse, Rat, Porcine, Monkey, Bovine, Hamster, Chicken, Dog, Frog
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	NTF3, NT3, HDNF, NGF2, NGF-2
Available
NCBI Gene ID	4908
Uniprot	P20783
Biological Activity	The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.
Description	NT-3 is a neurotrophic factor structurally related to ß-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues). Human and Mouse NT-3 sequences are identical
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	120
Molecular Weight	13.6 kDa
mRNA RefSeq	NM_001102654
Protein RefSeq	NP_001096124.1
Protein Sequence	MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	NTF3; NT3; HDNF; NGF2; NGF-2
Uniprot ID	P20783

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Amount: 2ug

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Delivery expected until 8/16/2024