FMK-9a

Item no.	MOLN-M13062-25mg
Manufacturer	Molnova
CASRN	1955550-51-2
Amount	25 mg
Category	Reagents & Chemicals Other Chemicals
Type	Chemicals
Specific against	other
Purity	>98% (HPLC)
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Brief description	FMK-9a (FMK9a) is a potent, selective, covalent peptidomimetic inhibitor of ATG4B (Autophagin-1) with IC50 of 80 nM in TR-FRET assay; displays no activity against the aspartic protease, serine proteases, metalloproteases and the 20S proteasome, inhibits cathepsin B and calpain with submicromolar IC50 (0.1-0.2 uM); covalently binds to Cys74 and inactivates ATG4B proteolytic activity, has an IC50 of 15 nM in the cellular LRA assay.
Formula Weight	392, 4229
Stability	≥ 2 years
Storage	(-20℃)
Receptor	Atg

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Amount: 25 mg

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Delivery expected until 9/27/2024