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LSN 3213128

LSN 3213128

Item no.	MOLN-M13043-200mg
Manufacturer	Molnova
CASRN	1941211-99-9
Amount	200 mg
Category	Reagents & Chemicals Other Chemicals
Type	Chemicals
Specific against	other
Purity	>98% (HPLC)
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Brief description	LSN 3213128 is a novel potent, selective and orally-bioavailable antifolate with potent and specific inhibitory activity for AICARFT; results in dramatic elevation of 5-aminoimidazole 4-carboxamide ribonucleotide (ZMP) and growth inhibition in NCI-H460 and MDA-MB-231met2 cancer cell lines; demonstrates tumor growth inhibition in a murine based xenograft model of triple negative breast cancer (TNBC); Aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT) is an enzyme in the purine biosynthetic pathway.
Formula Weight	409, 45
Stability	≥ 2 years
Storage	(-20℃)
Receptor	Antifolate

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Amount: 200 mg

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Delivery expected until 8/23/2024