PBIT

Item no.	M15089-50mg
Manufacturer	AbMole
CASRN	2514-30-9
Amount	50mg
Category	Reagents & Chemicals Other Chemicals
Type	Chemicals
Specific against	other
Purity	1
Formula	C14H11NOS
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Target Information	Histone demethylase
Molecular Weight	241, 31
Solubility	DMSO ≥ 40 mg/mL
Bioactivity information	PBIT is a JARID1 (Jumonji AT-Rich Interactive Domain 1) inhibitor with IC50 values of 3, 4.9 and 6 μM for JARID1B, 1A and 1C, respectively. It can increase trimethylation of H3K4 in HeLa cells and block the proliferation of tumor cells expressing high levels of JARID1B.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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