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αC-Conotoxin PrXA

αC-Conotoxin PrXA

Item no.	HY-P5149-1ea
Manufacturer	MedChem Express
Amount	1 ea
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	98.44
Citations	[1]Jimenez EC, et al. AlphaC-conotoxin PrXA: a new family of nicotinic acetylcholine receptor antagonists. Biochemistry. 2007 Jul 31;46(30):8717-24.
Smiles	O=C([C@H]1N(CCC1)C([C@H](CCCCN)NC([C@H](C)NC([C@H](CC(O)=O)NC([C@@H](NC([C@H]([C@@H](C)CC)NC(CNC([C@@H](NC([C@@H](N)[C@H](O)C)=O)CC2=CC=C(C=C2)O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)=O)N4[C@@H](C[C@H](C4)O)C(N[C@H](C(N[C@@H](CO)C(N[C@@H]5C(N[C@@H](C)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(NCC(N[C@@H](CSSC5)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N6[C@@H](CCC6)C(N7[C@@H](C[C@H](C7)O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N8[C@@H](C[C@H](C8)O)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(N)=O)CCC(O)=O)=O)=O)CC9=CC=CC=C9)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC%10=CC=CC=C%10)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	αC-PrXA
Available
Product Description	αC-Conotoxin PrXA is a paralytic peptide neurotoxin and a competitive nAChR antagonist, with IC50s of 1.8 nM (α1β1εδ, adult) and 3.0 nM (α1β1γδ, fetal), respectively. αC-Conotoxin PrXA competes with α-bungarotoxin at the α/δ and α/γ subunit interfaces of the nAChR, shows high specificity against neuromuscular nAChR[1].
StorageTemperature	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Shipping	Blue Ice
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	3541.06
Clinical_Information	No Development Reported
Manufacturers Research_Area	Neurological Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target	nAChR
Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Manufacturers Product type	Peptides

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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