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27-Methyl withaferin A

27-Methyl withaferin A

Item no.	HY-N10354-100mg
Manufacturer	MedChem Express
CASRN	1777780-93-4
Amount	100 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Citations	[1]Gabriel G Llanos, et al. Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers. Eur J Med Chem. 2017 Nov 10;140:52-64.
Smiles	C[C@]12[C@@]3([C@H](C=CC2=O)O)[C@](C[C@]4([H])[C@]1([H])CC[C@]5([C@@]4([H])CC[C@]5([H])[C@@H]([C@@]6([H])CC(C)=C(C(O6)=O)COC)C)C)([H])O3
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	27-Methyl withaferin A (comppund 26) is an apoptosis inducer with anticancer effects. 27-Methyl withaferin A shows antiproliferative effects against HeLa, A-549 and MCF-7 human tumor cell lines with IC50 values of 3.2 μM, 4.2 μM and 1.4 μM, respectively[1].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	484.62
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	10 mM in DMSO
Manufacturers Target	Apoptosis
Pathway	Apoptosis
Manufacturers Product type	Reference compound

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Amount: 100 mg

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