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Fmoc-Hyp(Bom)-OH

Fmoc-Hyp(Bom)-OH

Item no.	HY-79125-100mg
Manufacturer	MedChem Express
CASRN	187223-15-0
Amount	100 mg
Quantity options	100 mg 1 ea 1 g 500 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	98.0
Formula	C28H33N3O8
Citations	[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.<br/>[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
Smiles	O=C(O)[C@@H]1C[C@@H](OC(NCCNC(OC(C)(C)C)=O)=O)CN1C(OCC2C3=C(C=CC=C3)C4=C2C=CC=C4)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	Fmoc-Hyp(Bom)-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Hyp(Bom)-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs<
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	539.58
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	10 mM in DMSO
Target	ADC Linker; PROTAC Linkers
Manufacturers Target	ADC Linker; PROTAC Linkers
Isoform	Cleavable Linker
Manufacturers Pathway	Antibody-drug Conjugate/ADC Related; PROTAC
Manufacturers Product type	ADC Related

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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