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P2X7-IN-2 (TFA)

P2X7-IN-2 (TFA)

Item no.	HY-18725A-10mg
Manufacturer	MedChem Express
Amount	10 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Other Chemicals
Type	Reagents
Specific against	other
Purity	99.93
Formula	C24H22F7N3O4
Citations	[1]Kelly, Michael G, et al. Preparation of isoquinolonecarboxamides as P2X7 purinoceptor modulators and uses thereof. WO2008112205 A1. 2008.
Smiles	O=C(NC1=C(C)C=CC2=C1C=CN([C@H](C)CN)C2=O)CC3=CC=C(C(F)(F)F)C(F)=C3.O=C(O)C(F)(F)F
ECLASS 10.1	42051003
ECLASS 11.0	42051003
UNSPSC	12000000
Available
Product Description	P2X7-IN-2 TFA (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 TFA inhibits IL-Iβ release with an IC50 value of 0.01 nM. P2X7-IN-2 TFA can be used for the research of autoimmunity, inflammation and cardiovascular disease[1].
StorageTemperature	4°C (Powder, protect from light, stored under nitrogen)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	549.44
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology; Cardiovascular Disease
Solubility	DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Interleukin Related; P2X Receptor
Manufacturers Target	Interleukin Related; P2X Receptor
Manufacturers Pathway	Immunology/Inflammation; Membrane Transporter/Ion Channel
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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