TMX1

Item no.	HY-153385-25mg
Manufacturer	MedChem Express
Amount	25 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Other Chemicals
Type	Reagents
Specific against	other
Purity	99.09
Formula	C26H28N4O3S
Citations	[1]Li Y D, et al. Template-assisted covalent modification of DCAF16 enables BRD4 molecular glue degraders[J]. Cancer Research, 2023, 83(7_Supplement): 3424-3424.
Smiles	O=C/C=C/C1=CC=C(C2=N[C@@H](CC(OC(C)(C)C)=O)C3=NN=C(C)N3C4=C2C(C)=C(C)S4)C=C1
ECLASS 10.1	42051003
ECLASS 11.0	42051003
UNSPSC	12000000
Available
Product Description	TMX1 is a BRD4 covalent molecular glue degrader. TMX1 selectively recruits DCAF16 to BRD4BD2, resulting in the degradation of BRD4[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	476.59
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : ≥ 100 mg/mL
Target	Apoptosis; Epigenetic Reader Domain
Manufacturers Target	Apoptosis; Epigenetic Reader Domain
Manufacturers Pathway	Apoptosis; Epigenetics
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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