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KIF18A-IN-6

KIF18A-IN-6

Item no.	HY-153065-1ea
Manufacturer	MedChem Express
CASRN	2914879-10-8
Amount	1 ea
Category	Reagents & Chemicals Other Chemicals
Type	Chemicals
Specific against	other
Purity	98.56
Citations	[1]COGAN, et al. SPIRO INDOLINE INHIBITORS OF KIF18A. Patent WO2023028564.
Smiles	O=S(C1=CC(C(N2CC3(CCC4(CC4)CC3)C5=CC(NS(CC)(=O)=O)=CC=C52)=O)=CC=C1)(NC(C)(C)C)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	KIF18A-IN-6 (Compound 134) is an orally active KIF18A inhibitor with an IC50 of 0.016 μM against KIF18A microtubule-dependent ATPase activity[1].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	559.74
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 125 mg/mL (ultrasonic)
Manufacturers Target	Microtubule/Tubulin
Pathway	Cell Cycle/DNA Damage; Cytoskeleton
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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